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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. For research purposes only.
High-purity, structurally verified peptide sequences for advanced laboratory and pre-clinical applications.
Semaglutide is a synthetic analog of human glucagon-like peptide-1 (GLP-1) with 94% homology to native GLP-1. With the molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and a molecular weight of 4113.6 g/mol (CAS: 910...
Lab Verified
Clinical Grade
PMID Cited
Published preclinical research has characterized the following molecular pathways and receptor interactions for GLP-1(S).
Semaglutide binds to GLP-1 receptors with high affinity, activating Gs-proteins and increasing intracellular cAMP levels in beta-cell models (PMID: 30215696).
The C18 fatty di-acid side chain enables reversible albumin binding, extending circulation half-life in biochemical studies (PMID: 29015992).
Published studies indicate Semaglutide promotes receptor internalization with distinct kinetics compared to native GLP-1 (PMID: 31819012).
Lau et al. (2018) detailed the structure-based design of Semaglutide, including albumin binding modifications and GLP-1 receptor affinity (PMID: 30215696).
Capehorn et al. (2020) characterized Semaglutide's binding kinetics to GLP-1 receptors and receptor internalization properties in cell culture (PMID: 31819012).
RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
MetabolicC10H11N2 (free base) · 159.21 g/mol (free base)
For in vitro research use only. Not for human consumption.
MetabolicC9H14N4O5 · 258.23 g/mol
For in vitro research use only. Not for human consumption.
MetabolicC78H123N23O23S2 · 1815.12 g/mol
For in vitro research use only. Not for human consumption.