MOTS-c.

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a synthetic 16-amino acid peptide encoded in the mitochondrial genome. With the molecular formula C₁₀₁H₁₅₂N₂₈O₂₂S₂ and a molecular w...

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Lab Verified

Clinical Grade

PMID Cited

Mechanism of Action.

Published preclinical research has characterized the following molecular pathways and receptor interactions for MOTS-c.

AMP-activated protein kinase

AMPK Pathway

MOTS-c activates AMPK signaling, influencing cellular energy metabolism in muscle and fat cell models.

Fibroblast growth factor 21

FGF21 Expression

Research indicates MOTS-c increases FGF21 expression, affecting metabolic gene networks in adipose tissue cultures.

Evidence Based

Clinical Literature

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Preclinical

Research review on MOTS-c molecular characterization.

Preclinical studies have characterized the molecular properties and receptor binding profiles of MOTS-c in standardized assay systems.

Preclinical

MOTS-c structure-activity relationship analysis.

Structure-activity relationship studies have examined the functional domains and binding characteristics of MOTS-c in cell-free and cell-based systems.

RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.

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